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KMID : 0359720140320020113
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Journal of the Korean Neurological Association
2014 Volume.32 No. 2 p.113 ~ p.116
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Encephalopathy After Glufosinate Ammonium Intoxication
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Kim Jae-Hwan
Yu In-Woo
Kim Yong-Duk
Na Sang-Jun
Lee Kee-Ook
Yoon Bo-Ra
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Abstract
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Glufosinate ammonium is the active ingredient in broad-spectrum contact herbicides such as BASTAⓡ that inhibits the activity of glutamine synthetase, which is necessary for the production of the amino acid glutamine and for ammonia detoxification. Complications of glufosinate ammonium intoxication include gastrointestinal symptoms, loss of consciousness, convulsions, memory impairment, respiratory failure, and cardiovascular instability. We report herein a case of encephalopathy and reversible signal changes in the splenium of the corpus callosum, the bilateral corticospinal tracts, the hippocampi, and the cerebellar peduncles as seen in diffusion-weighted magnetic resonance imaging and fluid-attenuated inversion recovery images following BASTAⓡ intoxication.
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KEYWORD
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Glufosinate ammonium, Encephalopathy, Intoxication
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